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Acne Isotretinoin
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Acne Isotretinoin
Is Sotret (acne drug) less effective than other brands of Isotretinoin?
I've seen several blogs from people whose dermatologists prescribe Sotret for a few months, and then Claravis to end the Isotretinoin course, as if that packs a bigger punch.
I also watched a vlog from 2009 wherein a dermatologist claimed Sotret had been discovered to not contain standardized dosage of the actual drug, and so many people had to repeat treatment.
From my point of view, I"ve been prescribing Sotret for a few years now, and have not seen any difference in efficacy from what I am used to seeing when prescribing Accutane or Clarivis or Amnesteem.
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Acne: Therapy with Accutane (Isotretinoin)
Retinoid Creams for Acne Therapy
Topical retinoid creams can be used to treat acne. Many studies have shown that retinoid creams (also known as topical retinoids) are efficient in treating comedonal acne.
Topical tretinoin and isotretinoin (another form of tretionoin) are useful in treating patients with comedonal acne. Isotretinoin, also known by many people as the tradename Roaccutane, can also be taken orally in capsule form.
Tretionoin and isotretinoin are both licensed to treat mild to moderate acne. Isotretinoin is especially licensed to treat non-inflammatory/ inflammatory lesions in patients with mild to moderate acne.
Topical Tretinoin
This can be described as the acid form of Vitamin A. It usually goes by the tradename of Retin-A (Janssen-Cilag) and is a prescription only medication. That is, you can only obtain this cream, if your doctor prescribes it and thinks that you may benefit from it. Tretinoin can also be obtained in gel (Retin- A gel) or lotion (Retin-A lotion) form.
A formulation of tretinoin and erythromycin (an antibacterial) can be obtained. It goes by the tradename of Aknemycin Plus (Crookes).
Topical Isotretinoin
This is also an acid form of Vitamin-A, and can be described as an isomer of tretinoin (isomer is another form of the same substance). It can be obtained in two preparations. The first is called Isotrex (Stiefel) which is in the form of a gel and the second , is called Isotrexin (Stiefel) gel which contains isotretinoin plus an antibacterial called erythromycin.
Cautions
1.Topical retinoids should be avoided in severe acne involving large areas
2.Exposure to UV light should be avoided
3.Use of abrasives (facial exfoliators etc.) in conjunction with retinoid creams should be avoided
4.If using benzoyl peroxide, allow for skin peeling to subside before using topical retinoids
Contraindications
1.Should be avoided in during pregnancy
2.Tretinoin is contraindicated in personal or familial history of cutaneous epithelioma.
Side effects
1.Skin burning, redness, stinging, itching,
2.Dry peeling skin
3.Temporary changes of skin pigmentation have been reported but this is less common
4.Eye blistering (irritation and swelling around the eye) have been reported but rarely
Efficacy
The topical retinoids are good at keeping (mild to moderate) acne at bay but by no means are they 100% effective in all people using them. If you find that you acne has not started to improve after 1-2 months of treatment with the topical retinoids, then it may be good to consult your doctor so that other alternatives can be suggested.
Your physician may prescrib oral retinoids or topical antibacterials depending on which ever he/she thinks is suitable for you.
About the Author
Asanka Samaranayake (BSc Hons Neuroscience) and Darren Patten (Bsc Hons Surgery & Anaesthesia)have a specialist interest in microdermabrasion and provide you with an indispensable resource at Microdermabrasion Info. Net
6 things must be done EVERYDAY to reduce/prevent acne: 1)Wash, Tone, Moisturize Face 2 or 3 Times 2)Don't Let Dirty Things Touch Face 3)Eat Healthy Food, Limit Junk Food 4)Take Multi Vitamin Mineral 5)Drink About 64 oz Pure Water 6)Do 20 to 30 Min Aerobic Exercise. Doing 1 or a few of these will NOT keep skin clear as possible!
Must use 3 things on face: Wash, Toner, Moisturizer. Do this at least 2x a day, morning & night (possibly 3rd time, midday, if super oily/sweating). Products that work for one person may not work for another person, so always do small patch test on face for a couple of days to see how skin will react to product! Don't quickly jump from product to product! Give skin a break before trying new product to prevent irritation! Natural & gentle products are sometimes more effective than acne medicine!
NATURAL & GENTLE: Wash face with warm water & Purpose Gentle Cleansing Bar by Johnson & Johnson. Tone face with Witch Hazel (Thayers or Dickinson's) or Homemade Toner. Witch Hazel reduces bacteria/swelling, minimizes size of skin pores, helps acne. Make toner by mixing 1 part Organic Apple Cider Vinegar With The Mother (Bragg Organic Apple Cider) with 5 parts pure water. Test small area! If burns/to drying, use more water! Use at least 1 part water! Less Water = Stronger, More Drying Formula. This vinegar kills bacteria, absorbs excess oil, dries out pimples, lightens scars, refines skin tone. Don't use other types of vinegar, will damage skin! Moisturize face with Lily Of The Desert Aloe Vera Gelly, its 99% organic, contains vitamin A, C, E! Aloe vera helps renew skin cells, heals blemishes/scars. Don't use other brands of aloe, has very little aloe & to much junk in it which can irritate skin!
ACNE MEDICINE: Try 1 of these active ingredients for a period of time to see if skin improves: Benzoyl Peroxide, Salicylic Acid, Sulfur, Alpha Hydroxy Acid, Beta Hydroxy Acid, Lactic Acid, Glycolic Acid. Try acids by Perfect Peel Solutions, Cellbone Technology, Skin Laboratory, Alpha Hydrox/Neoteric Cosmetics. Acid heals acne, cyst, scars! If over the counter medicine doesn't work, see doctor to get stronger medicine.
FACE PRODUCTS & MAKEUP: Only use oil free products that won't clog pores! Using a Makeup Finish or Makeup Setting Spray (Skindinavia, Model In A Bottle, Sephora) will give you shine-free skin all day! Old makeup, makeup tools harbor bacteria, Use fresh makeup, wash/replace tools often! Wash makeup off face before going to bed!
FACE MASK can be done once a week. Make mask by mixing plain oatmeal with water. Oatmeal is soothing, absorbs excess oil, makes skin smoother. Wash face with warm water, apply mask. Leave on for 20 min or until it dries. Rinse off with warm water, Apply toner & moisturizer.
HANDS-HAIR-STUFF: Keep dirt & bacteria at bay to prevent more breakouts! Don't touch face with hands, Don't let phone nor dirty oily hair touch face, Don't lean face on objects, Clean glasses often, Wash pillowcase, sheets, blanket, washcloth, towel often. Always wash hands before applying face products!
KEEP MOVING: Aerobic Exercise, Face Massage, Dry Skin Brushing increases circulation & delivery of nutrients to skin cells, encourages good blood supply, helps remove toxins, controls acne breakouts! Do 20to30 min of exercise, everyday or every other day! For outstanding results, do all 3 activities, everyday! When exercising, drink water & immediately take a shower to remove sweat & dirt! For face massage, wash hands & face, apply toner, use aloe vera as massage gel. Do 10 min massage before going to bed. Don't wash face again, let aloe dry on face. Buy any book on face massage like the, Ten Minute Facelift by Jennie Harding. Dry Skin Brushing must be done correctly & carefully, read book, Dr. Berkowsky's Vital Chi Skin Brushing System by Bruce Berkowsky! Never brush delicate face! Take shower after brushing to wash off dead skin & dirt!
DIET & LIFESTYLE: Research has shown that there is a connection between certain kinds of food & acne! Read book The Clear Skin Diet by Alan C. Logan & Valori Treloar! This book has detailed info on what to eat and not to eat to help reduce/prevent acne! Always eat healthy food – fruit, vegetables, lean meat, fiber, beans, wholegrains, foods rich in omega 3 fatty acids, zinc, vitamin A & C. Limit intake of frozen meals, dairy, milk, fat, oil, butter, greasy/fried foods, sugar, candy, salt, dessert, caffeine, coffee, pop, alcohol. Always avoid cigarettes, tobacco, illegal drugs! Its hard to get all vitamins minerals skin needs, so take supplement everyday! Overdosing on vitamins minerals from food or supplements is dangerous! Drinking about 64 oz of pure water everyday improves skin quality, flushes out toxins, delivers nutrients to skin! You can also include 100% Fruit Juice as part of your daily total. Acne can be caused or aggravated by constipation, make sure bow movements are regular! Getting enough sleep helps skin repair itself!