Erythromycin Topical Acne

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Erythromycin Topical Acne

Has Anyone ever tried Erythromycin for Acne?

I got this prescription for acne and the bottle name is "Erythromycin Benzoyl Peroxide Topical Gel" Has anyone ever tried it? if so how do u use it? and what are their side effects? does it even work?

How should you take Erythromycin, Benzoyl peroxide?

Use Benzamycin 2 times per day, once in the morning and once in the evening, or as directed by your doctor.

Before applying Benzamycin, thoroughly wash the affected area with soap and warm water, rinse well, and gently pat dry. Apply Benzamycin to the entire area, not just the pimples.

* If you miss a dose...
Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.

* Storage instructions...
This medication should be stored in your refrigerator in a tightly closed container and discarded after 3 months. Do not freeze.

What side effects may occur?

Very few side effects have been reported with the use of Benzamycin. However, those reported include dryness and swelling. Occasionally, use of Erythromycin, Benzoyl peroxide has caused a burning sensation; eye irritation; inflammation of the face, eyes, and nose; itching; oiliness; reddened skin; skin discoloration; skin irritation and peeling; and skin tenderness.

If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Benzamycin.

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Acne Topical Retinoid Therapy

Until the retinoids became available, there wasn't anything that really affected comedonal acne. Theoretically, if you prevent the formation of the precursor, you prevent all the subsequent lesions from forming. That probably can occur if you can get enough of the right retinoid, either systemically or topically.

Retinoic acid binds to all three kinds of retinoid receptors: alpha, beta, and gamma. It is thought that the gamma receptor is the most important in the pathogenesis of acne, and retinoic acid has a very high affinity for gamma receptors. First of all, there is sebum. Sebum itself might be comedogenic, but whether it is or not, it certainly provides the nutrient material for P acnes. The proliferation of this microorganism is the next pathogenic factor.

In addition to reversing abnormal keratinization, there is evidence that the topical retinoids may have some anti-inflammatory properties. Both adapalene (Differin®) and tretinoin have been shown to do this in different experiments. Because Retin-A has been on the market for more than 25 years, patients will frequently come in and say, "I've already used tretinoin; it didn't work." For many physicians, their first inclination is to try something else. My favorite therapy is a topical retinoid used in conjunction with a combination of benzoyl peroxide and erythromycin.

Or I might use one of the newer benzoyl peroxides, such as benzoyl peroxide mixed with zinc and glycolic acid. With moderate to moderate/severe inflammatory acne, I would probably think about systemic antibiotics. If the patient is a woman, one might consider using birth control pills as acne therapy. Everyone should use sunscreens all the time.

I recommend a minimum sun protection factor (SPF) of 15 or greater. Patients should apply their topical acne therapy first thing in the morning, and then put on the sunscreen before they go outside. I recommend moisturizers for patients who are experiencing irritation from topical therapy.

I tend to encourage them to use the lighter moisturizers, rather than heavier ones, and to use only those that have been tested and are labeled as noncomedogenic or nonacnegenic. Unemployment is much greater in patients with acne than in people who don't have acne. That increases with the severity of disease.

I recommend moisturizers for patients who are experiencing irritation from topical therapy. I tend to encourage them to use the lighter moisturizers, rather than heavier ones, and to use only those that have been tested and are labeled as noncomedogenic or nonacnegenic.

Significant inflammation is the primary one. With moderate to moderate/severe inflammatory acne, I would probably think about systemic antibiotics. If the patient is a woman, you might consider using birth control pills as acne therapy.

Acne Topical Retinoid Therapy

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